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Helical Tomotherapy

Helical Tomotherapy Versus Conventional Radiation to Deliver Abdominopelvic Radiation (49-56)

While whole abdominopelvic radiation (APRT) provided satisfactory radiation dosimetry for the treatment of cancers with peritoneal dissemination, APRT was abandoned due to unsatisfactory tumor control from necessary radiation shielding of vital organs. Our goal was to develop a helical tomotherapy (TOMO) abdominopelvic radiation technique improving target tissue coverage while dose-limiting vital organs, especially hematopoietic bone marrow. This study reports our clinical development of a TOMO abdominopelvic radiation technique for treatment of patients with advanced stage ovarian cancer. Novel chemoradiosensitizing agent clinical trials incorporating our TOMO abdominopelvic radiation technique for treatment of patients with recurrent ovarian cancer are under development.

Key words: Whole abdomen irradiation; Helical tomotherapy.





This article can be cited as:
Choe, J., Kulasekere, R. Oddo, D., Anthony, S., Shin, T., Murray, M., Kunos, C.A.. Helical Tomotherapy Versus Conventional Radiation to Deliver Abdominopelvic Radiation Technol Cancer Res Treat. 11, 49-56 (2012). DOI: 10.7785/tcrt.2012.500234

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This article can be accessed at PubMed:
http://www.ncbi.nlm.nih.gov/pubmed/22181331

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Received: January 11, 2011; Revised: July 20, 2011; Accepted: July 21, 2011

TCRT February 2012

category image
Volume 11
No.1 (1-104)
February 2012
ISSN 1533-0338

DOI: 10.7785/tcrt.2012.500234

J. Choe, M.D.1
R. Kulasekere, Ph.D.1
D. Oddo, C.M.D.1
S. Anthony, C.M.D.1
T. Shin1
M. Murray, C.M.D.1
C. A. Kunos, M.D., Ph.D.1*

1Department of Radiation Oncology and Case Comprehensive Cancer Center, University Hospitals Case Medical Center and Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA

*Phone: 216-844-3103
Fax: 216-844-2005
charles.kunos@UHhospitals.org