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Cyberknife Radiosurgery for Squamous Cell Carcinoma of Vulva After Prior Pelvic Radiation Therapy (p. 375-380)

Limited options exist for patients experiencing a local recurrence of vulvar malignancies after surgery and pelvic radiation. These recurrences often are associated with cancer-related skin desquamation and poor clinical outcomes. A new radiotherapeutic treatment modality for the previously irradiated patient is cyberknife radiosurgery, which uses a linear accelerator mounted on an industrial robotic arm to allow non-coplanar radiation therapy delivery with sub-millimeter precision. This study describes the first reported use of cyberknife radiosurgery for the treatment of recurrent vulvar cancer in three women.

Key words: Vulvar cancer; Cyberknife radiosurgery.

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TCRT October 2008

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Volume 7
No. 5 (p 341-414)
October 2008
ISSN 1533-0338

Charles Kunos, MD, Ph.D.1,*
Vivian von Gruenigen, MD2
Steven Waggoner, MD2
James Brindle, Ph.D.1
Yuxia Zhang, MS1
Brenda Myers, RTT1
Gary Funkhouser, RTT1
Barry Wessels, Ph.D.1
Douglas Einstein, MD, Ph.D.1

1Department of Radiation Oncology and Department of Obstetrics and Gynecology
2Division of Gynecological Oncology
University Hospitals of Cleveland Case Medical Center and Case Western Reserve University
Cleveland, OH 44106, USA