TCRT August 2006

category image Volume 5
No. 4 (p 299-444)
August 2006
ISSN 1533-0338

In Vivo MRI Electrical Impedance Tomography (MREIT) of Tumors (p. 381-388)

A significant increase in electrical conductivity of neoplasticities compared to healthy tissues and benign formations has been reported in several studies. We previously reported preliminary results with MR based Electrical Impedance Tomography (MREIT) on several phantoms and a single animal. In the presented study, we applied the technique on ten tumor-bearing rats and collected MREIT images to investigate the potential of MREIT for characterizing malignant tumors. Results show that the tumors had significantly higher mean conductivity compared to the mean of conductivity in the rest of the body. Although heterogeneity of conductivity was observed in the tumor, the mean was still higher than the background.

Keywords: MREIT; Electrical Impedance Tomography; MRI; and Cancer imaging.

L. Tugan Muftuler, Ph.D.
Mark J. Hamamura, Ph.D.
Ozlem Birgul, Ph.D.
Orhan Nalcioglu, Ph.D.

John Tu & Thomas Yuen Center for Functional Onco-Imaging
University of California
164 Irvine Hall
Irvine, CA 92697-5020, USA
*muftuler@uci.edu

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