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Cancer Watch

Thermoacoustic and Photoacoustic Tomography of Thick Biological Tissues Toward Breast Imaging (p. 559-566)

Microwave-based thermoacoustic tomography (TAT) and laser-based photoacoustic tomography (PAT) in a circular scanning configuration were both developed to image deeply seated lesions and objects in biological tissues. Because malignant breast tissue absorbs microwaves more strongly than benign breast tissue, cancers were imaged with good spatial resolution and contrast by TAT in human breast mastectomy specimens. Based on the intrinsic optical contrast between blood and chicken breast muscle, an embedded blood object that was 5 cm deep in the tissue was also detected using PAT at a wavelength of 1064 nm.




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TCRT October 2005

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Volume 4
No. 5 (p 455-582)
October 2005
ISSN 1533-0338

Geng Ku, Ph.D.1
Bruno D. Fornage, M.D.2
Xing Jin, M.S.1
Minghua Xu, Ph.D.1
Kelly K. Hunt, M.D.3
Lihong V. Wang, Ph.D.1,*

1Optical Imaging Laboratory
Department of Biomedical Engineering
Texas A&M University
3120 TAMU
College Station, TX 77843-3120, USA
2Departments of Diagnostic Radiology and Surgical Oncology
The University of Texas
M. D. Anderson Cancer Center
Houston, TX 77030, USA
3Department of Surgical Oncology
The University of Texas
M. D. Anderson Cancer Center
Houston, TX 77030, USA
*LWang@tamu.edu