TCRT December 2004

category image Volume 3
No. 6 (p 525-670)
December 2004
ISSN 1533-0338
Breast Cancer

The Role of Magnetic Resonance Imaging in Diagnosis and Management of Breast Cancer (p. 527-542)

A review of the literature on the current applications of breast magnetic resonance imaging (MRI) indications, their rationale and their place in diagnosis and management of breast cancer was given. Contrast-enhanced breast MRI is developing as a valuable adjunct to mammography and sonography. Its high sensitivity for invasive breast cancer establishes its superiority in evaluation of multifocality/multicentricity, tumor response to neoadjuvant chemotherapy, detection of recurrence, and staging. Emerging applications include spectroscopy, usage of new contrast agents, and MRI-guided interventions, including noninvasive treatment of breast cancer. Its potential benefit in screening high-risk women has yet to be established with prospective studies, particularly with regard to false positive results.

Key words: Breast cancer, Magnetic resonance imaging, MRI-guided intervention, Cancer screening.

Dag Pavic, M.D.*
Marcia A. Koomen, M.D.
Cherie M. Kuzmiak, D.O.
Y. H. Lee, M.D., Ph.D.
Etta D. Pisano, M.D.

Department of Radiology
University of North Carolina at Chapel Hill Medical School
CB 7510, 101 Manning Dr.
Chapel Hill, NC 27599 USA
*Dag_Pavic@med.unc.edu

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