Cancer remains a devastating disease worldwide, with more than 10 million new cases and more than 6 million cancer-related deaths reported each year (1). In addition, cancer prevalence is expected to continue to increase into the foreseeable future. Although great strides have been made with a variety of treatment modalities such as radiation, surgery, and chemotherapy, there is not only ample room for improvement, but also an urgent need to develop new strategies that will be applicable to large numbers of patients. Furthermore, cancer prevention by immunization with tumor antigens, altered tumor cells, or other innovative alternative approaches needs to be more fully explored.